Match ends, Roma 2, Lyon 1.
Roma fell just short of a comeback as Lyon knocked them out in the Europa League last 16.
The second-placed Serie A side trailed 5-2 on aggregate when Mouctar Diakhaby headed the French side into the lead on the night.
But Kevin Strootman prodded home an immediate equaliser and a Lucas Tousart own goal narrowed the gap but Roma could not find a late strike to take them through on away goals.
Edin Dzeko fired a late chance over.
Schalke came from 2-0 down, and 3-1 on aggregate, to beat Bundesliga rivals Borussia Monchengladbach on away goals.
Andreas Christensen and Mahmoud Dahoud had put Gladbach in control before Leon Goretzka's strike and Nabil Bentaleb's penalty.
Ryan Babel scored his first two European goals since 2010 as 10-man Besiktas beat Olympiakos 4-1 in Istanbul, 5-2 on aggregate.
Celta Vigo, Spain's only representatives left in the tournament, beat FK Krasnodar 2-0 in Russia to progress 4-1 overall.
Bertrand Traore and Kasper Dolberg scored as Ajax beat FC Copenhagen 2-0 to overturn a 2-1 first-leg deficit to progress.
Anderlecht beat Apoel Nicosia 1-0 (2-0 on aggregate), while Genk beat fellow Belgians Gent 6-3 on aggregate after a 1-1 second-leg draw.
Manchester United beat FC Rostov 1-0 to go through 2-1 overall.
Line-ups
Roma
Formation 3-1-4-2
- 19Alisson
- 44ManolasBooked at 21mins
- 20Fazio
- 2Rüdiger
- 16De RossiSubstituted forTottiat 84'minutes
- 13da Silva PeresSubstituted forEl Shaarawyat 59'minutes
- 6StrootmanBooked at 38mins
- 4NainggolanBooked at 61mins
- 21Mário RuiSubstituted forPerottiat 76'minutesBooked at 89mins
- 11Salah
- 9Dzeko
Substitutes
- 1Szczesny
- 3Nunes Jesus
- 5Paredes
- 8Perotti
- 10Totti
- 33Emerson
- 92El Shaarawy
Lyon
Formation 4-2-3-1
- 1LopesBooked at 86mins
- 13Jallet
- 4MammanaBooked at 70minsSubstituted forYanga-Mbiwaat 78'minutes
- 5Diakhaby
- 15Morel
- 29TousartBooked at 28mins
- 21GonalonsBooked at 85mins
- 27Cornet
- 8Tolisso
- 28ValbuenaSubstituted forPereira da Silvaat 90+1'minutes
- 10LacazetteSubstituted forFekirat 84'minutes
Substitutes
- 2Yanga-Mbiwa
- 11Ghezzal
- 12Ferri
- 14Darder
- 18Fekir
- 20Pereira da Silva
- 30Gorgelin
- Referee:
- Viktor Kassai
Match Stats
- Possession
- Home61%
- Away39%
- Shots
- Home25
- Away8
- Shots on Target
- Home9
- Away4
- Corners
- Home11
- Away4
- Fouls
- Home17
- Away20
Live Text
Post update
Full Time
Second Half ends, Roma 2, Lyon 1.
Post update
Offside, Lyon. Anthony Lopes tries a through ball, but Nabil Fekir is caught offside.
Post update
Attempt blocked. Stephan El Shaarawy (Roma) left footed shot from the centre of the box is blocked. Assisted by Edin Dzeko.
Post update
Attempt blocked. Stephan El Shaarawy (Roma) right footed shot from the centre of the box is blocked. Assisted by Francesco Totti.
Post update
Corner, Roma. Conceded by Lucas Tousart.
Post update
Attempt blocked. Edin Dzeko (Roma) right footed shot from the centre of the box is blocked. Assisted by Stephan El Shaarawy with a cross.
Post update
Antonio Rüdiger (Roma) wins a free kick in the defensive half.
Post update
Foul by Nabil Fekir (Lyon).
Post update
Corner, Lyon. Conceded by Kevin Strootman.
Post update
Corner, Lyon. Conceded by Alisson.
Post update
Attempt saved. Nabil Fekir (Lyon) right footed shot from the right side of the box is saved in the bottom right corner. Assisted by Christophe Jallet.
Post update
Attempt missed. Edin Dzeko (Roma) header from the centre of the box is just a bit too high. Assisted by Diego Perotti with a cross.
Substitution
Substitution, Lyon. Rafael replaces Mathieu Valbuena.
Post update
Kevin Strootman (Roma) wins a free kick in the defensive half.
Post update
Foul by Nabil Fekir (Lyon).
Booking
Diego Perotti (Roma) is shown the yellow card.
Post update
Foul by Antonio Rüdiger (Roma).
Post update
Maxwel Cornet (Lyon) wins a free kick on the right wing.
Post update
Attempt missed. Stephan El Shaarawy (Roma) right footed shot from the centre of the box is too high following a corner.